Jones & Bartlett Learning (JBL) Module 3 Practice Exam

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In evidence-based practice, what does PICO stand for?

Problem, Intervention, Cost, Outcome

Population, Idea, Choice, Observation

Person, Input, Control, Output

Patient/Population, Intervention, Comparison, Outcome

PICO is the framework used to structure a clinical question in evidence-based practice. It helps you specify four elements: the patient or population you’re concerned about (with relevant characteristics), the intervention or exposure being considered, the comparison condition or alternative, and the outcome you want to measure or achieve. This clarity makes it easier to search for evidence and to appraise what you find, because you can turn each element into search terms and test how well the results address the exact question. The standard expansion is Patient/Population, Intervention, Comparison, Outcome. The other options use terms that don’t align with how clinical questions are framed, so they wouldn’t guide a focused search or meaningful comparison in the same way. For example, think of a question like: in adults with hypertension, does an ACE inhibitor (I) compared with a beta-blocker (C) reduce systolic blood pressure (O)?

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